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1

Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis

Jane V. Higdon, Barbara Delage, David E. Williams, Roderick H. Dashwood

Journal:

Pharmacological Research

Year:

2007

Language:

english

File:

PDF, 397 KB

english, 2007

2

MicroRNAs, diet, and cancer: New mechanistic insights on the epigenetic actions of phytochemicals

Mansi A. Parasramka, Emily Ho, David E. Williams, Roderick H. Dashwood

Journal:

Molecular Carcinogenesis

Year:

2012

Language:

english

File:

PDF, 746 KB

english, 2012

3

Multi-targeted prevention of cancer by sulforaphane

John D. Clarke, Roderick H. Dashwood, Emily Ho

Journal:

Year:

2008

Language:

english

File:

PDF, 205 KB

english, 2008

4

Inside front cover: Comparison of anti-inflammatory mechanisms of mango ( Mangifera Indica L.) and pomegranate ( Punica Granatum L.) in a preclinical model of colitis

Kim, Hyemee, Banerjee, Nivedita, Ivanov, Ivan, Pfent, Catherine M., Prudhomme, Kalan R., Bisson, William H., Dashwood, Roderick H., Talcott, Stephen T., Mertens-Talcott, Susanne U.

Journal:

Molecular Nutrition & Food Research

Year:

2016

File:

PDF, 293 KB

2016

5

Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

Praveen Rajendran, Emily Ho, David E Williams, Roderick H Dashwood

Journal:

Clinical Epigenetics

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

6

Chemopreventive properties of chlorophylls towards aflatoxin B1: a review of the antimutagenicity and anticarcinogenicity data in rainbow trout

Roderick Dashwood, Tomoe Negishi, Hikoya Hayatsu, Vibeke Breinholt, Jerry Hendricks, George Bailey

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1998

Language:

english

File:

PDF, 533 KB

english, 1998

7

Cancer Chemopreventive Mechanisms of Tea Against Heterocyclic Amine Mutagens from Cooked Meat

Roderick H. Dashwood, Meirong Xu, Judith F. Hernaez, Nahidh Hasaniya, Kristi Youn, Aziz Razzuk

Journal:

Proceedings of The Society for Experimental Biology and Medicine

Year:

1999

Language:

english

File:

PDF, 54 KB

english, 1999

8

Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout

Michael T. Simonich, Tammie McQuistan, Carole Jubert, Cliff Pereira, Jerry D. Hendricks, Michael Schimerlik, Benzan Zhu, Roderick H. Dashwood, David E. Williams, George S. Bailey

Journal:

Food and Chemical Toxicology

Year:

2008

Language:

english

File:

PDF, 314 KB

english, 2008

9

Inhibition of β-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H2O2 at physiologically relevant EGCG concentrations

Wan-Mohaiza Dashwood, Gayle A Orner, Roderick H Dashwood

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 194 KB

english, 2002

10

Epigenetic Regulation by Sulforaphane: Opportunities for Breast and Prostate Cancer Chemoprevention

Atwell, Lauren L., Beaver, Laura M., Shannon, Jackilen, Williams, David E., Dashwood, Roderick H., Ho, Emily

Journal:

Current Pharmacology Reports

Year:

2015

Language:

english

File:

PDF, 350 KB

english, 2015

11

Measuring Histone Deacetylase Inhibition in the Brain

Reddy, Doodipala Samba, Wu, Xin, Golub, Victoria M., Dashwood, W. Mohaiza, Dashwood, Roderick H.

Journal:

Current Protocols in Pharmacology

Year:

2018

Language:

english

File:

PDF, 242 KB

english, 2018

12

Study of the forces stabilizing complexes between chlorophylls and heterocyclic amine mutagens

Roderick Dashwood, Shane Yamane, Randy Larsen

Journal:

Environmental and Molecular Mutagenesis

Year:

1996

Language:

english

File:

PDF, 699 KB

english, 1996

13

Effects of tea and chlorophyllin on the mutagenicity of N-hydroxy-IQ: Studies of enzyme inhibition, molecular complex formation, and degradation/scavenging of the active metabolites

Judith Hernaez, Meirong Xu, Roderick Dashwood

Journal:

Environmental and Molecular Mutagenesis

Year:

1997

Language:

english

File:

PDF, 89 KB

english, 1997

14

Frequent mutations of the rat β-catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1-hydroxyanthraquinone

Masumi Suzui, Toshikazu Ushijima, Roderick H. Dashwood, Naoki Yoshimi, Takashi Sugimura, Hideki Mori, Minako Nagao

Journal:

Molecular Carcinogenesis

Year:

1999

Language:

english

File:

PDF, 172 KB

english, 1999

15

Antimutagenic activity of spearmint

Tian-Wei Yu, Meirong Xu, Roderick H. Dashwood

Journal:

Environmental and Molecular Mutagenesis

Year:

2004

Language:

english

File:

PDF, 306 KB

english, 2004

16

Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: Studies with sulforaphane and garlic organosulfur compounds

Hui Nian, Barbara Delage, Emily Ho, Roderick H. Dashwood

Journal:

Environmental and Molecular Mutagenesis

Year:

2009

Language:

english

File:

PDF, 273 KB

english, 2009

17

Chlorophyllin-enhanced excretion of urinary and fecal mutagens in rats given 2-amino-3-methylimidazo[4, 5-f]quinoline

Roderick Dashwood, Christina Liew

Journal:

Environmental and Molecular Mutagenesis

Year:

1992

Language:

english

File:

PDF, 591 KB

english, 1992

18

Antimutagenic potency of chlorophyllin in the salmonella assay and its correlation with binding constants of mutagen-inhibitor complexes

Roderick Dashwood, Dexin Guo

Journal:

Environmental and Molecular Mutagenesis

Year:

1993

Language:

english

File:

PDF, 604 KB

english, 1993

19

E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin

Korakod Chimploy, G. Dario Díaz, Qingjie Li, Orianna Carter, Wan-Mohaiza Dashwood, Christopher K. Mathews, David E. Williams, George S. Bailey, Roderick H. Dashwood

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 370 KB

english, 2009

20

NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Rong Wang, Wan-Mohaiza Dashwood, Hui Nian, Christiane V. Löhr, Kay A. Fischer, Naoto Tsuchiya, Hitoshi Nakagama, Hassan Ashktorab, Roderick H. Dashwood

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 609 KB

english, 2011

21

The synthesis of [3H] - indole-3-carbinol, a natural anti-carcinogen from cruciferous vegetables

Roderick H. Dashwood, Lyle Uyetake, Arthur T. Fong, Jerry D. Hendricks, George S. Bailey

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1989

Language:

english

File:

PDF, 234 KB

english, 1989

22

Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: Mutational ‘hotspots’ and the relative expression of β-catenin and c-jun

Carmen A. Blum, Tomoko Tanaka, Xiaoying Zhong, Qingjie Li, Wan-Mohaiza Dashwood, Clifford Pereira, Meirong Xu, Roderick H. Dashwood

Journal:

Molecular Carcinogenesis

Year:

2003

Language:

english

File:

PDF, 243 KB

english, 2003

23

Dietary agents as histone deacetylase inhibitors

Melinda C. Myzak, Emily Ho, Roderick H. Dashwood

Journal:

Molecular Carcinogenesis

Year:

2006

Language:

english

File:

PDF, 109 KB

english, 2006

24

Evidence for ras gene mutation in 2-amino-3-methylimidazo[4,5-f]quinoline–induced colonic aberrant crypts in the rat

Nicholas Tachino, Rick Hayashi, Christina Liew, George Bailey, Roderick Dashwood

Journal:

Molecular Carcinogenesis

Year:

1995

Language:

english

File:

PDF, 457 KB

english, 1995

25

Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

John D. Clarke, Anna Hsu, Zhen Yu, Roderick H. Dashwood, Emily Ho

Journal:

Molecular Nutrition & Food Research

Year:

2011

Language:

english

File:

PDF, 460 KB

english, 2011

26

Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly

Praveen Rajendran, Barbara Delage, W Mohaiza Dashwood, Tian-Wei Yu, Bradyn Wuth, David E Williams, Emily Ho, Roderick H Dashwood

Journal:

Molecular Cancer

Year:

2011

Language:

english

File:

PDF, 1.65 MB

english, 2011

27

Promoter de-methylation ofcyclin D2by sulforaphane in prostate cancer cells

Anna Hsu, Carmen P Wong, Zhen Yu, David E Williams, Roderick H Dashwood, Emily Ho

Journal:

Clinical Epigenetics

Year:

2011

Language:

english

File:

PDF, 382 KB

english, 2011

28

Metabolism and Tissue Distribution of Sulforaphane in Nrf2 Knockout and Wild-Type Mice

John D. Clarke, Anna Hsu, David E. Williams, Roderick H. Dashwood, Jan F. Stevens, Masayuki Yamamoto, Emily Ho

Journal:

Pharmaceutical Research

Year:

2011

Language:

english

File:

PDF, 328 KB

english, 2011

29

Inhibitory Activity of Green and Black Tea in a Free Radical-generating System Using 2-Amino-3-methylimidazo[4,5-f]quinoline as Substrate

Nahidh Hasaniya, Kristi Youn, Meirong Xu, Judith Hernaez, Roderick Dashwood

Journal:

Year:

1997

File:

PDF, 362 KB

1997

30

β-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet

Rong Wang, W. Mohaiza Dashwood, Christiane V. Löhr, Kay A. Fischer, Hitoshi Nakagama, David E. Williams, Roderick H. Dashwood

Journal:

Year:

2008

Language:

english

File:

PDF, 367 KB

english, 2008

31

Introduction to Nutrition and Physical Activity in Aging, Obesity, and Cancer

Young-Joon Surh, Roderick H. Dashwood, Hye-Kyung Na, Li Li Ji

Journal:

Annals of the New York Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 150 KB

english, 2011

32

Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates

Roderick H Dashwood, Emily Ho

Journal:

Nutrition Reviews

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

33

Phosphorylation and ubiquitination of oncogenic mutants of β-catenin containing substitutions at Asp32

Al-Fageeh, Mohamed, Li, Qingjie, Mohaiza Dashwood, W, Myzak, Melinda C, Dashwood, Roderick H

Journal:

Year:

2004

Language:

english

File:

PDF, 321 KB

english, 2004

34

Antimutagenic activity of selenium-enriched green tea toward the heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline

Adams Amantana, Gilberto Santana-Rios, Judith A. Butler, Meirong Xu, Phil D. Whanger, Roderick H. Dashwood

Journal:

Biological Trace Element Research

Year:

2002

Language:

english

File:

PDF, 198 KB

english, 2002

35

Chemopreventive properties of chlorophyllin: inhibition of aflatoxin B1 (AFB1)-DNA binding in vivo and anti-mutagenic activity against AFB1 and two heterocyclic amines in the salmonella mutagenicity assay

Dashwood, Roderick H., Breinholt, Vibeke, Bailey, George S.

Journal:

Year:

1991

Language:

english

File:

PDF, 386 KB

english, 1991

36

Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells

Daejoong Kwon, Sun Yoon, Orianna Carter, George S. Bailey, Roderick H. Dashwood

Journal:

Year:

2006

Language:

english

File:

PDF, 240 KB

english, 2006

37

MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach

Mansi A. Parasramka, W. Mohaiza Dashwood, Rong Wang, Amir Abdelli, George S. Bailey, David E. Williams, Emily Ho, Roderick H. Dashwood

Journal:

Molecular Nutrition & Food Research

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

38

Chlorophyllin Chemoprevention in Trout Initiated by Aflatoxin B1 Bath Treatment: An Evaluation of Reduced Bioavailability vs. Target Organ Protective Mechanisms

Vibeke Breinholt, Dan Arbogast, Pat Loveland, Cliff Pereira, Roderick Dashwood, Jerry Hendricks, George Bailey

Journal:

Toxicology and Applied Pharmacology

Year:

1999

Language:

english

File:

PDF, 102 KB

english, 1999

39

Anticarcinogenesis in fish

George Bailey, Jerry Hendricks, Roderick Dashwood

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1992

Language:

english

File:

PDF, 588 KB

english, 1992

40

Mechanisms of the in vitro antimutagenic action of chlorophyllin against benzo[a]pyrene: Studies of enzyme inhibition, molecular complex formation and degradation of the ultimate carcinogen

Nicholas Tachino, Dexin Guo, Wan Mohaiza Dashwood, Shane Yamane, Randy Larsen, Roderick Dashwood

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1994

Language:

english

File:

PDF, 890 KB

english, 1994

41

Modulation of diethylnitrosamine-induced hepatocarcinogenesis and O6-ethylguanine formation in rainbow trout by indole-3-carbinol, β-naphthoflavone, and Aroclor 1254

Arthur T. Fong, Jerry D. Hendricks, Roderick H. Dashwood, Samina Van Winkle, Brian C. Lee, George S. Bailey

Journal:

Toxicology and Applied Pharmacology

Year:

1988

Language:

english

File:

PDF, 733 KB

english, 1988

42

Endurance exercise results in DNA damage as detected by the comet assay

Angela Mastaloudis, Tian-Wei Yu, Robert P. O'Donnell, Balz Frei, Roderick H. Dashwood, Maret G. Traber

Journal:

Free Radical Biology and Medicine

Year:

2004

Language:

english

File:

PDF, 498 KB

english, 2004

43

Capsaicin represses transcriptional activity of β-catenin in human colorectal cancer cells

Seong-Ho Lee, Raphael L. Richardson, Roderick H. Dashwood, Seung Joon Baek

Journal:

The Journal of Nutritional Biochemistry

Year:

2012

Language:

english

File:

PDF, 1.18 MB

english, 2012

44

Lysosomal trafficking of β-catenin induced by the tea polyphenol epigallocatechin-3-gallate

Wan-Mohaiza Dashwood, Orianna Carter, Mohamed Al-Fageeh, Qingjie Li, Roderick H. Dashwood

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2005

Language:

english

File:

PDF, 683 KB

english, 2005

45

Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in β-catenin that are independent of β-catenin mutation status

Rong Wang, W. Mohaiza Dashwood, George S. Bailey, David E. Williams, Roderick H. Dashwood

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2006

Language:

english

File:

PDF, 688 KB

english, 2006

46

Dietary histone deacetylase inhibitors: From cells to mice to man

Roderick H. Dashwood, Emily Ho

Journal:

Seminars in Cancer Biology

Year:

2007

Language:

english

File:

PDF, 994 KB

english, 2007

47

Indole-3-carbinol: Anticarcinogen or tumor promoter in brassica vegetables?

Roderick H Dashwood

Journal:

Chemico-Biological Interactions

Year:

1998

Language:

english

File:

PDF, 60 KB

english, 1998

48

Response of Apcmin and A33ΔNβ-cat mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Gayle A Orner, Wan-Mohaiza Dashwood, Carmen A Blum, G.Darı́o Dı́az, Qingjie Li, Mohamad Al-Fageeh, Niall Tebbutt, Joan K Heath, Matthias Ernst, Roderick H Dashwood

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2002

Language:

english

File:

PDF, 249 KB

english, 2002

49

Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and β-catenin/Tcf signaling

Carmen A. Blum, Meirong Xu, Gayle A. Orner, G. Darı&amp, #x0301, o Dı&amp, #x0301, az, Qingjie Li, Wan Mohaiza Dashwood, George S. Bailey, Roderick H. Dashwood

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2003

Language:

english

File:

PDF, 246 KB

english, 2003

50

Use of fish and fish transgenics in laboratory and field genotoxicology studies

Roderick H. Dashwood, George S.Robert Bailey

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1998

File:

PDF, 256 KB

1998